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Thread: The 'Ask Dan a Question' thread!

  1. #61
    Steroidal.com Writer/Mod Dan C's Avatar
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    Quote Originally Posted by BEAR View Post
    FYI / UPDATE........

    Electra recently stopped birth control because she was having a problem with Estrogen deposits around her lower tummy & the back / inside of her arms, yes the anabolic cycle has definately disrupted her menstrual cycle / ovulation...........BUT...........(notice the BIG BUT..........I like big buts.........) while we are both pretty secure in the theory that she can't get pregnant right now.........we still take a little extra precaution............I don't "finish" inside her..........with my sperm count lowered & her ovulation disrupted...........we're confident in this technique.................

    "I'm just sayin......."
    Awesome update, thanks for sharing. I have had women tell me that when they go on birth control, they find that they do gain weight as well as hold extra fat on the prototypical female areas (breasts, thighs, ass, etc.). I think that's pretty typical of what Estrogen does cause in the body in terms of fat distribution. The bulk of the weight gain is likely mostly water though. When they go off, I am told a lot of that recedes/disappears. There's no doubt that an anabolic steroid cycle in a female would disrupt ovulation, but how effective that is in comparison to birth control, I don't know. I think it's time for me to search some studies on this and see if such a thing has been studied at any point.
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  2. #62
    Member Bull's Avatar
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    Dan, what are your thoughts on HGH and insulin sensitivity? I've seen a study stating after 6 months of HGH use, insulin sensitivity/resistance were not affected. Seems as though from nearly everywhere else, it's said it increases the resistance. Trying to get this cleared up.

    Unable to link the study right now as I'm posting from my phone.

  3. #63
    Steroidal.com Writer/Mod Dan C's Avatar
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    Quote Originally Posted by Bull View Post
    Dan, what are your thoughts on HGH and insulin sensitivity? I've seen a study stating after 6 months of HGH use, insulin sensitivity/resistance were not affected. Seems as though from nearly everywhere else, it's said it increases the resistance. Trying to get this cleared up.

    Unable to link the study right now as I'm posting from my phone.
    What was the study you found? Can you link or reference it?

    I haven't studied too much on the diabetogenic effects of HGH. It seems to be something that has been parroted over the decades, yes, and even the medical establishment lists warnings concerning HGH use and how it will affect insulin sensitivity. I would imagine it's much like anything... within a certain dose range, it will probably have little to no effect, while going high enough on the dose would impact insulin sensitivity negatively. These are the things to pay attention to in the studies you come across. What was the dose used? For how long? Under what conditions? The fact that HGH plays a role in metabolism in the body dictates to me that it's very possible that there would be a negative impact on insulin sensitivity, but perhaps only at very high (i.e. pro/competitive bodybuilder doses) and for extended durations of use. I'm going to have to do some more research on this myself.
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  4. #64
    Member Bull's Avatar
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    Quote Originally Posted by Dan C View Post
    What was the study you found? Can you link or reference it?

    I haven't studied too much on the diabetogenic effects of HGH. It seems to be something that has been parroted over the decades, yes, and even the medical establishment lists warnings concerning HGH use and how it will affect insulin sensitivity. I would imagine it's much like anything... within a certain dose range, it will probably have little to no effect, while going high enough on the dose would impact insulin sensitivity negatively. These are the things to pay attention to in the studies you come across. What was the dose used? For how long? Under what conditions? The fact that HGH plays a role in metabolism in the body dictates to me that it's very possible that there would be a negative impact on insulin sensitivity, but perhaps only at very high (i.e. pro/competitive bodybuilder doses) and for extended durations of use. I'm going to have to do some more research on this myself.
    I found the study again and it turns it it was conducted on Growth hormone Deficient patients and didn't mention anything about insulin sensitivity, only amount of insulin. That's what I get for researching at the end of a night shift. I'd be glad to hear of anything you come across in your research on this though.

  5. #65
    VET warmouth's Avatar
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    What level of hepatoxicity do you thimk there is if using 35mgs of dbol for 4 weeks while taking highish amiunts of acetaminophen daily? I understand this would increase the risk, but if using 1200mgs of NAC daily, could it be controlled? Right now I use 600mgs of NAC and my liver enzymes are amazing. And you know what they used to be. I am taking accutane that finally ends in a week and yet my liver enzymes and function is amazing. BTW, I'm not planning using dbol anytime soon, just curious more than anything. I may never use it to be honest. I am planning on running a moderate dose of Anavar as a bridge (like 60-75mgs), but Anavar really only effects my lipids, and effects them bad. Ill be looking into something to help that, but am more curious about the dbol. One thing at a time
    What say you?

  6. #66
    Steroidal.com Writer/Mod Dan C's Avatar
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    While I think 600mg of NAC daily should be adequate, i'd bump it up to 1200, maybe even 1800. I've used as much as 2400mg of NAC before with no issues. I am assuming you saw the recent update on my liver thread/article? The study I referenced where it was discovered extreme doses of NAC can exhibit lung and heart issues used doses far in excess of what we would use. I was actually going to suggest in my update that a NAC dose for liver repair after extensive liver damage could be up in the 3,000 - 4,000 mg range, but I wanted to play it safe as the last thing I need is a bunch of kids think they can use extreme doses of NAC and end up with heart and lung issues.

    Anyhow, I think in your case you should be good to go. If you want added security, you can use TUDCA with it, and you'd have the AAS cholestasis specific to the oral AAS covered, and the NAC would have the acetaminophen toxicity covered (as well as overlapping the anti-cholestasis effect of the TUDCA). But as long as you're getting bloodwork (and you are), you will know where your liver enzymes are at, and as long as they're good and in perfect range there's no need to spend money on an extra protectant if everything is already okay.

    As far as Anavar and it's effects on lipids go, I would suggest supplementing with 4g of fish oil per day while on cycle. In fact, I suggest doing that on ANY and ALL cycles. I find the best combination is something like 3g of fish oil and 1g of flax seed oil, and you have everything taken care of. NAC should improve liver values while using oral C17AA anabolic steroids, and TUDCA should help it even better. Anavar doesn't seem to affect most people's lipids too harshly, but your body seems to have an exceptional individualized reaction. In fact, if I remember correctly from some bloodwork you showed me a while ago, you've always had issues with bad lipids regardless of on-cycle or off-cycle, so I am not surprised even Anavar would have such a negative effect.
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  7. #67
    VET warmouth's Avatar
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    Thank you for the detailed answer. Definitley helped and made me a bit more secure. Dbols hepatoxicity has always freaked me out a bit, but I will run NAC at 1200mgs and tudca at 500 I guess to be on the safe side if I do run it. And I do take 4grams of fish oil daily now, and have been for about 6 months. I may up it an extra gram with the flaxseed. Great stuff. You need to write a book!

  8. #68
    VET warmouth's Avatar
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    Here is something that's been on my mind for a good while now. I have someone very close who is on trt. This guy is 52 and has RA and fibromyalgia. Most days, due to pain and depression, it is a chore for him to even get out of bed. It is debilitating and I hate to see what is happening. I've been thinking of some things to do to try to help with both pain and emotions. His trt is gel ad his doc won't change it. So I have been thinking about a blend of test/Nandrolone with long esters for his trt in
    hopes it might possibly help most of BBC his aliments. Even on trt gel, his levels are under 300 and estradiol is high. I was thinking about a once a week pin of a 100/100 blend. Do you think the Nandrolone is dosed too high at 100mgs for the reason I am wanting to do this? I'm hoping to keep everything low enough to keep from using any ancillaries, yet high enough to help.

  9. #69
    Steroidal.com Writer/Mod Dan C's Avatar
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    I think that's a solid plan. There are a lot of TRT clinics in the States that prescribe Testosterone and Nandrolone at doses much higher than that, actually. Try it out and see how it goes for him.

    This just demonstrates a complete lack of initiative and any thoughtfulness on the part of the medical establishment, when doctors don't know a thing about TRT (or are too afraid to touch Testosterone) to the point where they won't attempt anything other than the gel/cream. I know a few people who attempted TRT through their doctors, they hated the gel and requested injectables instead, and the doctor refused. So now they just self-administer injectable TRT. Kind of pathetic when people have to take their own TRT into their own hands because their physicians can't actually do their jobs.
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  10. #70
    VET warmouth's Avatar
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    Quote Originally Posted by Dan C View Post
    I think that's a solid plan. There are a lot of TRT clinics in the States that prescribe Testosterone and Nandrolone at doses much higher than that, actually. Try it out and see how it goes for him.

    This just demonstrates a complete lack of initiative and any thoughtfulness on the part of the medical establishment, when doctors don't know a thing about TRT (or are too afraid to touch Testosterone) to the point where they won't attempt anything other than the gel/cream. I know a few people who attempted TRT through their doctors, they hated the gel and requested injectables instead, and the doctor refused. So now they just self-administer injectable TRT. Kind of pathetic when people have to take their own TRT into their own hands because their physicians can't actually do their jobs.
    That is my exact same situation. For both me and this person I'm talking about. The gel made both of our free and total T drop lower than before, yet neither of our doctors would prescribe anything else. It sucks resorting to this, but it works. So you think the 100:100 ratio pinned once a week wouldbe suficient and not high enough to use ancillaries or caber?

  11. #71
    Steroidal.com Writer/Mod Dan C's Avatar
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    Quote Originally Posted by warmouth View Post
    That is my exact same situation. For both me and this person I'm talking about. The gel made both of our free and total T drop lower than before, yet neither of our doctors would prescribe anything else. It sucks resorting to this, but it works. So you think the 100:100 ratio pinned once a week wouldbe suficient and not high enough to use ancillaries or caber?
    Yeah, there shouldn't be a need for ancillaries or Cabergoline. Ideally, bloodwork would be the best thing to do so as to monitor levels and make sure you and your friend are exactly where you want to be, but I know this isn't an option in most situations like these.
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  12. #72
    VET warmouth's Avatar
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    Quote Originally Posted by Dan C View Post
    Yeah, there shouldn't be a need for ancillaries or Cabergoline. Ideally, bloodwork would be the best thing to do so as to monitor levels and make sure you and your friend are exactly where you want to be, but I know this isn't an option in most situations like these.
    True. The person is my dad, I just didn't want to outright say it. He is always in pain to the point of not having a desire to live most days. He is no longer able to work and is depressed about that as well. Went fron a thriving business to nothing, and no savings worth mentioning. I want to help him, but dont want to make anything worse on him. I just feel if he had normal test levels and a little Nandrolone, he might feel like a new man. Might even drop a few pounds of bodyfat.

  13. #73
    Member Bull's Avatar
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    Dan, what protocol would you recommend for HCG during a cycle to keep the boys up, while reducing the risk of Estrogen and chance of over-stimulating? You got me worried in the HCG thread the other day. I would get flares of Estrogen during my last cycle, after every shot of HCG. I can't have that for my next cycle as I have a show in the middle of it. Adex, Letro, or aromosin didn't help that much. Letro did slightly, but it killed my knees. Also, it only seemed to happen towards the end of my cycle.

  14. #74
    Steroidal.com Writer/Mod Dan C's Avatar
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    All of that is covered in the HCG profile: HCG (Human Chorionic Gonadotropin) | Steroidal.com just go to the HCG Dosage section.

    As you'll read throughout that profile, you'll see that HCG does indeed express estrogenic activity through its ability to increase aromatase enzyme production through stimulation of the cells in the testes. That's why I recommended in the profile to always run HCG with Aromasin if possible, in order to prevent Estrogen related sides. Also, if you don't use Aromasin with HCG, your HPTA won't actually recover properly, since Estrogen also works via the negative feedback loop and will stop the hypothalamus from releasing GnRH just as bad (or worse) as excess androgens do. By not keeping the aromatase enzyme in check when using HCG, you can actually serve to set yourself back because of that.

    Was the Aromasin you used UGL/research or pharm grade? Most UGL's don't even put Aromasin in their tablets. It's difficult to say how many do or don't but many don't. Aromasin should always work the best, and Arimidex and Letro should also work to prevent Estrogen increases from HCG administration. I wonder if your ancillaries were good to go in your case.
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  15. #75
    VET warmouth's Avatar
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    Here is one to possibly stump you Dan. But knowing you, you'll have an immediate answer. A friend of mine (female) ran a 10mg Anavar cycle, then took 4 weeks off, then jumped on a 15mgs Anavar cycle. Its been 3 months since she had a period, and its been 3 weeks since she finished her Anavar cycle. She had a normal period the first cycle, then spotted the last. Now nothing. 8 pregnancy tests later, all negative. I told her its bound to be some type of hormone rebound and that time should fix the problem. She has stayed off the BC pills and is now planning on restarting them. She feels she needs her period now, and rightfully so. Do you have any insight I might be able to forward to her to give her some relief? Thanks buddy!

  16. #76
    Steroidal.com Writer/Mod Dan C's Avatar
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    Yeah sounds like her menstrual cycle is still thrown off from the Anavar. Some women can take months recovering after a cycle. My suggestion would be start the birth control, run it for a bit, then stop it and see if the cycle returns to normal. That should assist in resetting the cycle, kind of like a PCT for women. If that doesn't work, I have no clues at the moment due to the fact that female AAS use and how the female body responds is a whole different ballgame from men.

    Worst case if that idea doesn't work would be to try Clomid or HCG.
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  17. #77
    VET warmouth's Avatar
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    Quote Originally Posted by Dan C View Post
    Yeah sounds like her menstrual cycle is still thrown off from the Anavar. Some women can take months recovering after a cycle. My suggestion would be start the birth control, run it for a bit, then stop it and see if the cycle returns to normal. That should assist in resetting the cycle, kind of like a PCT for women. If that doesn't work, I have no clues at the moment due to the fact that female AAS use and how the female body responds is a whole different ballgame from men.

    Worst case if that idea doesn't work would be to try Clomid or HCG.
    Sweet! Thanks man. Passing this on.

  18. #78
    Member Bull's Avatar
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    Quote Originally Posted by Dan C View Post
    All of that is covered in the HCG profile: HCG (Human Chorionic Gonadotropin) | Steroidal.com just go to the HCG Dosage section.

    As you'll read throughout that profile, you'll see that HCG does indeed express estrogenic activity through its ability to increase aromatase enzyme production through stimulation of the cells in the testes. That's why I recommended in the profile to always run HCG with Aromasin if possible, in order to prevent Estrogen related sides. Also, if you don't use Aromasin with HCG, your HPTA won't actually recover properly, since Estrogen also works via the negative feedback loop and will stop the hypothalamus from releasing GnRH just as bad (or worse) as excess androgens do. By not keeping the aromatase enzyme in check when using HCG, you can actually serve to set yourself back because of that.

    Was the Aromasin you used UGL/research or pharm grade? Most UGL's don't even put Aromasin in their tablets. It's difficult to say how many do or don't but many don't. Aromasin should always work the best, and Arimidex and Letro should also work to prevent Estrogen increases from HCG administration. I wonder if your ancillaries were good to go in your case.
    Thanks for the info Dan. My ancillaries are legit. I think it was just the doses I was using. If I remember right, it was 700mg+ of test and 500mg+ of tren. I also only got them a little after my gyno started. It stopped it from getting worse except for a flare up that lasted a day, after every HCG shot. But I will try running Aromasin through the whole cycle this time around.

  19. #79
    Junior Member DrBPackenwood's Avatar
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    what's the point in running PCT for 4+ weeks?

    i mean, the point of PCT is to get your body producing natty test again.. so say your body is back to producing test again after 2 weeks of PCT, what's the point of continuing PCT after that??

    just wondering is all...

    thanks

  20. #80
    Founding Member OdinsOtherSon's Avatar
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    I am investigating Triptorelin as a potential replacement for HCG in this role, since it has the added benefit of keeping the pituitary stimulated as well as the Leydig cells of the testes. This would keep two points of the axis from undergoing atrophy from prolonged dormancy due to the negative feedback loop. HCG use only really tackles the Leydig cells, but not the pituitary. Thought i'd mention that since we're on this topic already.
    Dan, just curious as to your progress in the Triptorelin investigation. Cheers!

  21. #81
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    Dan, I need your knowledge again. As you know, I'm running CJC DAC 500mcg/w with huperzine 400-500mcg/day. I'm concerned about the effects of all that GH on my t3 and t4. I know very little of both of those, or how they relate. There's too much contradictory information for me out there and i dont have to time to search through it all now. Could there be an inhibitory effect? And if so, would you recommend t3 even off cycle to combat it? Low dose perhaps?

  22. #82
    Steroidal.com Writer/Mod Dan C's Avatar
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    Quote Originally Posted by DrBPackenwood View Post
    what's the point in running PCT for 4+ weeks?

    i mean, the point of PCT is to get your body producing natty test again.. so say your body is back to producing test again after 2 weeks of PCT, what's the point of continuing PCT after that??

    just wondering is all...

    thanks
    It is just simply to assure your HPTA is functioning properly again. The fact is that there are those who have a lot of difficulty recovering, and require a PCT of 6 or more weeks, and there are those who bounce back after 2 - 4 weeks of PCT. The only way to know for certain is with bloodwork, and even then, you need to have the bloodwork done at LEAST 8 weeks after all PCT compounds have been stopped. If you get bloodwork done too soon after PCT, then you won't get a proper reading due to the fact that the PCT meds are still having an impact on the HPTA. When you get bloodwork done, it should be done so as to see how the body is functioning on its own capacity WITHOUT the assistance of PCT meds. Getting bloodwork done during or too soon after PCT will always demonstrate extremely high Testosterone levels for obvious reasons. But in general, the 4 - 6 week minimum rule for PCT length is just the way it is so that we can assure the HPTA has been stimulated long enough to function properly on its own capacity again, and that seems to be the average time frame required for the average individual to be fully recovered.

    Quote Originally Posted by OdinsOtherSon View Post
    Dan, just curious as to your progress in the Triptorelin investigation. Cheers!
    Won't be able to report back on that until about 2 - 3 months from now, but do some google searches in the meantime and you'll find some very interesting stuff. Just google "Triptorelin for PCT" and "Triptorelin on cycle" and watch what you find. Interesting stuff.

    Quote Originally Posted by Bull View Post
    Dan, I need your knowledge again. As you know, I'm running CJC DAC 500mcg/w with huperzine 400-500mcg/day. I'm concerned about the effects of all that GH on my t3 and t4. I know very little of both of those, or how they relate. There's too much contradictory information for me out there and i dont have to time to search through it all now. Could there be an inhibitory effect? And if so, would you recommend t3 even off cycle to combat it? Low dose perhaps?
    I too have read conflicting info on changes in T3 during HGH use. Now, the thing is, you're talking about endogenous HGH, which the body could have a different response to than exogenous HGH. I honestly can't give a conclusive answer on this one because of the conflicting info out there, and the fact that you're simply boosting endogenous HGH levels rather than putting exogenous HGH into yourself. I just tried to do a quick search of any studies that observe changes in T3 in relation to changes in somatotropin, and I couldn't find anything. It seems to be 'common' knowledge that supraphysiological doses of HGH over the long term might suppress T3 secretion (and/or conversion of T4 to T3), but by how much? I don't know. And I doubt it stays like that after you stop using HGH or CJC-1295. I wouldn't recommend supplementing with T3, as I think the impacts are negligible UNLESS you have bloodwork done and are seeing that your T3 levels have significantly reduced following HGH or CJC-1295 administration. Bloodwork is the key here, and the only way you will be able to tell if something you suspect is going on is really going on.
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  23. #83
    VET warmouth's Avatar
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    For bulking, would you use 750mgs og test E with 600ish Nandrolone deconate,or 750mgs of test E with 600mgs of NPP weekly? I hate using long esters to cycle, especially the deconate, but will NPP used in this fashion give me similar results I'd used for 6 on, 4 off (while using the test still) then using the NPP for 6 more? Planning on a 16 weeker. I really hate the Deca esters kick in time. Last time it took about 8 weeks to kick in.

  24. #84
    Steroidal.com Writer/Mod Dan C's Avatar
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    Yes long esters are disliked a great deal by myself as well, they have very long half-lives and therefore require a lot of time to reach peak steady optimal blood plasma levels, especially the extremely long esters like Decanoate. Anyhow, the use of NPP would be very similar to Testosterone Propionate vs Testosterone Enanthate.
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  25. #85
    VET warmouth's Avatar
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    Well heck man. I know we are all on the low test kick right now, and I do love it, but would you agree that higher test is a god bet, wether ran alone or in a stack) would be a better option that using NPP or anything else for that matter, with a low test, high primary? NPP and Tren are difficult bulking agents due to the mechanisms or action, but the low test/high primary is amazing for cutting. I know the "biggest" I ever got was on test P, but these days I'd need a large dose, hence me needing to stack a bit. Thanks Dan!

  26. #86
    Junior Member KIWI's Avatar
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    Hey there Dan, what's your opinion/thoughts on running tren and Deca together (with test). I have used both compounds in the past (separately with test) in the past with no sides apart from a few night sweats while on the tren.

    Maybe

    500mgs test
    250mg tren
    250mg Deca

    I would be using Aromasin/Adex with HCG on cycle. Have got nolva and caber in the cupboard. Never had any issues with any type of gyno in the past

    Any type of supplements you recommend on this type of cycle.

    My apologies if this question already asked. Thanks.
    Last edited by KIWI; 08-16-2013 at 07:43 PM.

  27. #87
    Steroidal.com Writer/Mod Dan C's Avatar
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    I know that running Trenbolone and Deca has been done before by some, but it is something recommended for experienced guys only. You really need to know your body. Trenbolone and Deca are both 19-nor Progestins, and running both of them would have a larger impact on the Progesterone receptor, which might exacerbate Estrogen-related side effects (if you are prone to it/them). At the end of the day, when it comes to this, you need to be experienced in how you reacted to Trenbolone and Deca in previous cycles (meaning you have to have run both of them before, obviously). I would keep a Prolactin antagonist on hand, such as Cabergoline or Pramipexole (even vitamin B6 works) in case Prolactin issues might arise as well, so good thing you have Cabergoline stored away.

    I think you're good to go.
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  28. #88
    Junior Member nicco's Avatar
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    Nicotinic acid for better cholesterol

    Quote Originally Posted by warmouth View Post
    Thank you for the detailed answer. Definitley helped and made me a bit more secure. Dbols hepatoxicity has always freaked me out a bit, but I will run NAC at 1200mgs and tudca at 500 I guess to be on the safe side if I do run it. And I do take 4grams of fish oil daily now, and have been for about 6 months. I may up it an extra gram with the flaxseed. Great stuff. You need to write a book!
    My cholesterol levels are genetically bad- Average HDL and high LDL. I started taking Omega 3-6-9 at 6 caps daily . 2 caps contain 800 mg borage oil, 800 mg fish oil concentrate, Flax seed oil 800 mg. Also take 500 mg time released nicotinic acid. This significantly increased my HDL and reduced LDL somewhat. Although my total cholesterol is still high as compared to norms, my LDL/HDL ratio is pretty good. I take this on and off cycles. BTW I'm 7 weeks into my second cycle. Have not checked levels yet but will do soon and post. the nicotinic acid helped me a lot - I did before and after bloodwork. But lets see the result while I am on juice...

  29. #89
    VET warmouth's Avatar
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    Quote Originally Posted by nicco View Post
    My cholesterol levels are genetically bad- Average HDL and high LDL. I started taking Omega 3-6-9 at 6 caps daily . 2 caps contain 800 mg borage oil, 800 mg fish oil concentrate, Flax seed oil 800 mg. Also take 500 mg time released nicotinic acid. This significantly increased my HDL and reduced LDL somewhat. Although my total cholesterol is still high as compared to norms, my LDL/HDL ratio is pretty good. I take this on and off cycles. BTW I'm 7 weeks into my second cycle. Have not checked levels yet but will do soon and post. the nicotinic acid helped me a lot - I did before and after bloodwork. But lets see the result while I am on juice...
    Nicotinic acid......What is the common name for it if I were to purchase it? I don't believe that I have ever heard of this before. Thanks!

  30. #90
    Steroidal.com Writer/Mod Dan C's Avatar
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    Nicotinic acid is Niacin, also known as Vitamin B3!
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