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Thread: Fish Oil the Anti-Inflammotory

  1. #1
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    Mar 2013

    Fish Oil the Anti-Inflammotory

    Brain Behav Immun. 2012 Nov;26(8):1265-72. doi: 10.1016/j.bbi.2012.08.002. Epub 2012 Aug 10.
    Fish oil supplementation augments post-exercise immune function in young males.

    Gray P, Gabriel B, Thies F, Gray SR.

    Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.



    Fish oils and related fatty acid components have anti-inflammatory properties, with beneficial effects against various disorders such as cardiovascular disease. A single bout of exercise can alter immune function. However, the effects of fish oil on immune function after a single bout of exercise are currently unknown. This study investigated the effect of supplementation with fish oil on the immune response to an acute bout of endurance exercise.

    Sixteen male subjects underwent a six week double blind randomised placebo controlled supplementation trial involving two groups (fish oil or placebo oil, 3g/day). They attended for two visits, the first involving a maximal exercise test and the second involving a 1-h bout of endurance exercise on a cycle ergometer at 70% (V)O(2peak). Blood samples were taken pre-supplementation, pre-exercise (post-supplementation), immediately, 1 and 3h post-exercise. Samples were analysed for plasma IL-6, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and cortisol; peripheral blood mononuclear cell (PBMC) IL-2, IL-4 and IFN-γ production; neutrophil phagocytosis/oxidative burst; and natural killer (NK) cell cytotoxic activity.

    Post-supplementation EPA concentration was increased (P=0.0127) in the fish oil group. At 3h post-exercise PBMC IL-2 (P=0.0067) and NK cell activity (P=0.0163) was greater in the fish oil compared with the control group. However, PBMC IL-4 and IFN-γ productions, plasma IL-6 and cortisol concentrations, as well as neutrophil activity were unaffected by fish oil supplementation.

    The current study demonstrates that fish oil supplementation reduces increases PBMC IL-2 production and NK cell cytotoxic activity in the recovery period after exercise.
    Copyright 2012 Elsevier Inc. All rights reserved.

    PMID: 22902522 [PubMed - indexed for MEDLINE]

    Fish oil supplementation augments post-exe... [Brain Behav Immun. 2012] - PubMed - NCBI

  2. #2
    Junior Member
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    Oct 2013
    Hi Admin,
    Informative post on fish oil and like to add fish oil lose and maintain healthy body weight, prevents from joint pains and great for brain functions. Fish oil reduce cholesterol level and prevents from depression, hypertension, heart and cardio disease. Fish oil improves our vision and mood.

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